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February 7, 2020February 7, 2020

Asian Mothers with JIA Aren’t at Greater Risk of Pregnancy Complications, Study Finds

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Asian mothers with juvenile idiopathic arthritis (JIA) are not at greater risk of pregnancy- or birth-related complications than mothers without the disorder, a study found. The study, “Pregnancy outcomes ... Read more

February 4, 2020February 4, 2020

More Gingivitis Inflammation, Altered Oral Microbiome in JIA Patients, Study Finds

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Although children with juvenile idiopathic arthritis (JIA) have good dental health overall, they experience more gum inflammation caused by gingivitis than do healthy children, a study found. In addition, ... Read more

January 31, 2020January 31, 2020

Liver, Spleen, Lymph Nodes Can Help Distinguish Acute Lymphoblastic Leukemia from JIA, Study Says

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An enlarged liver and spleen and swollen lymph nodes are telltale signs that can help physicians distinguish acute lymphoblastic leukemia (ALL) from juvenile idiopathic arthritis (JIA) in children with ... Read more

January 28, 2020January 28, 2020

JIA Children Have Lower Levels of Enzymes that Suppress Gene Activity, Study Suggests

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Children with juvenile idiopathic arthritis (JIA), particularly boys, have significantly lower levels of DNA methyltransferases (DNMTs) — specific enzymes that suppress gene activity without changing their sequence — than healthy ... Read more

January 24, 2020January 24, 2020

Off-label Use of Xeljanz and Olumiant Effective Against Eye Inflammation in JIA, Case Study Shows

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Off-label use of Xeljanz and Olumiant effectively treated uveitis — a form of eye inflammation — and was well-tolerated by four patients with juvenile idiopathic arthritis (JIA) who had ... Read more

January 21, 2020January 21, 2020

Combined Testing of Inflammatory Biomarkers and Clinical Info Helps Predict Short-term JIA Activity, Study Finds

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Testing five blood biomarkers while taking into account clinical characteristics of children with newly diagnosed juvenile idiopathic arthritis (JIA) can help predict their disease activity in the short term, ... Read more

January 17, 2020January 17, 2020

Long-term Use of Biologic Therapies for sJIA Are Safe, Study Finds

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Long-term use of biologic therapies in people with systemic-onset juvenile idiopathic arthritis (sJIA) is acceptably safe, with varying rates of infections and macrophage activation syndrome depending on choice of ... Read more

January 14, 2020January 14, 2020

Local Steroid Injection Treats Tear Gland Inflammation Found in JIA Patient, Study Reports

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People with juvenile idiopathic arthritis (JIA) may develop dacryoadenitis, or inflammation of the tear-producing glands of the eye, a case report found. Dacryoadenitis can be effectively treated with a ... Read more

January 10, 2020January 10, 2020

Orofacial Pain in JIA Patients Linked to Disease Activity, Stress, and Daily Limitations, Study Reports

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People with juvenile idiopathic arthritis (JIA) who experience orofacial pain — pain in the mouth, face, and jaw — have more stress, limitations on daily activities, disease activity, and systemic inflammation ... Read more

January 7, 2020January 7, 2020

Early DMARD Treatment Improves Quality of Life for Children with Polyarticular JIA, Study Suggests

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Early aggressive treatment with biologic and synthetic disease-modifying anti-rheumatic drugs (DMARDs) improved the quality of life of children with polyarticular juvenile idiopathic arthritis (pJIA) in Finland, according to one-year data ... Read more

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