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October 1, 2019October 1, 2019

Parents’ Fear Of Their Children Experiencing Pain Reduces Adherence to JIA Treatments, Study Suggests

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Parents’ fear of their children experiencing pain can reduce treatment adherence in children with juvenile idiopathic arthritis (JIA), a new study suggests. The study, titled “Parent Pain Cognitions and Treatment ... Read more

September 27, 2019September 27, 2019

IL-6 a Potential Prognostic Biomarker in Systemic Juvenile Idiopathic Arthritis, Study Finds

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Levels of the inflammatory signaling molecule interleukin 6 (IL-6) in the blood may be a useful prognostic tool for systemic juvenile idiopathic arthritis (SJIA), a study suggests. The study, “Correlations ... Read more

September 24, 2019September 24, 2019

No Wrist Damage with Early JIA Treatment Targeting Inactive Disease, Trial Finds

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Children with recent-onset juvenile idiopathic arthritis (JIA) did not show signs of wrist damage over two years of treatment targeting inactive disease, according to a clinical trial in the Netherlands. ... Read more

September 20, 2019September 20, 2019

Arava May Be Viable Alternative for Methotrexate-intolerant JIA Patients, Study Says

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Arava (leflunomide) may be a viable alternative for reducing disease activity for patients with juvenile idiopathic arthritis who are intolerant to methotrexate, a study finds. The results, “Leflunomide treatment in ... Read more

September 17, 2019September 17, 2019

Pain Sensitivity in JIA Patients May Be Linked to Their History of Joint Inflammation, Study Says

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Human patients and rat models of juvenile idiopathic arthritis have unique thresholds of pain sensitivity, which is most likely related to their history of disease activity and joint inflammation rather ... Read more

September 10, 2019September 10, 2019

Tocilizumab Safe, Effective to Treat Very Young Systemic JIA Patients, Phase 1 Trial Shows

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Intravenous administration of tocilizumab at a dose of 12 mg/kg is safe and effective to treat systemic juvenile idiopathic arthritis patients who are younger than 2, results from a Phase ... Read more

September 6, 2019September 6, 2019

Physicians Should Be on Lookout for MAS Indicators in Children With sJIA, Study Says

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Variations in the levels of two proteins — ferritin and fibrinogen — at the time of a systemic juvenile idiopathic arthritis diagnosis may be early warning signs of macrophage activation ... Read more

September 3, 2019September 3, 2019

Study Notes Manitoba JIA Patients’ Suboptimal Access to Specialized Care

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A population-based study in the Canadian province of Manitoba has shown that up to 49% of patients with juvenile idiopathic arthritis (JIA) had not been seen by a pediatric rheumatologist ... Read more

August 30, 2019August 30, 2019

Infections Rare in JIA Children Treated with Biological Agents, Study Finds

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Developing infections as a side effect of juvenile idiopathic arthritis treatment with biological agents is rare — and in most cases, such infections are either mild or moderate in severity, ... Read more

August 23, 2019August 23, 2019

Major Pregnancy Complications Not Greater in DMARD Users, Study Finds

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Use of disease-modifying anti-rheumatic drugs (DMARDs) before becoming pregnant does not increase the risk of miscarriage or birth defects in women with juvenile idiopathic arthritis (JIA), or female partners ... Read more