News

January 18, 2019January 18, 2019

Walking Problems May Persist in Children Even as Inflammation Eases Over Time, Study Finds

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Knee and ankle joint inflammation and walking difficulties in children and adolescents with juvenile idiopathic arthritis (JIA) tends to decrease and stabilize in the first five years after diagnosis, a ... Read more

January 15, 2019January 15, 2019

Boys with Early JIA Have Greater Deficit of IGF-1 than Girls, Study Shows

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Boys with early juvenile idiopathic arthritis (JIA) have lower levels of insulin-like growth factor 1, a growth hormone, compared to age-matched girls in the same stage of early disease, a ... Read more

January 11, 2019January 11, 2019

Arterial Stiffness in Adults with Lasting Juvenile Idiopathic Arthritis Linked to Prednisolone, Insulin Resistance

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Adults with long-lasting juvenile idiopathic arthritis have altered arterial properties related to cardiovascular risk, such as arterial stiffness, mainly linked to daily prednisolone and insulin resistance, new findings show. The ... Read more

January 8, 2019January 8, 2019

Children with JIA May Reach Inactive Disease After Treatment-to-Target Strategy, Trial Shows

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More than 70% of children with juvenile arthritis may achieve complete drug-free inactive disease (DFID) following a tightly controlled treatment-to-target strategy, a study finds. The study, “Treat to target (drug-free) ... Read more

January 3, 2019January 3, 2019

Ilaris May Safely Lead Long-Term Clinical Remission in SJIA Patients, Extension Study Shows

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Ilaris (canakinumab) can reduce disease activity or lead to clinical remission of active systemic juvenile idiopathic arthritis (sJIA) for up to five years with no changes in its safety profile, a ... Read more

December 21, 2018December 21, 2018

Vitamin D Deficiency Linked to Higher Disease Activity in Juvenile Arthritis, Study Finds

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Vitamin D deficiency is common among patients with juvenile idiopathic arthritis and linked to higher disease activity and other medical complications, a study finds. The study, “Vitamin D deficiency is associated ... Read more

December 14, 2018December 14, 2018

Rituximab May Be Effective for JIA Patients Unresponsive to TNF Blockers, Study Shows

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Rituximab may be an effective treatment option for children and young people with juvenile idiopathic arthritis (JIA) who do not respond to tumor necrosis factor (TNF) inhibitors, showing a low rate ... Read more

December 7, 2018December 7, 2018

S100A12 May Be Potential Prognostic Biomarker in Juvenile Idiopathic Arthritis, Study Suggests

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The protein S100A12 can potentially be used as a biomarker for disease activity and a therapy’s effectiveness in juvenile idiopathic arthritis, a study found. The study, “A Granulocyte-Specific Protein S100A12 ... Read more

November 30, 2018November 30, 2018

FDA Approves Genentech’s Actemra Autoinjector For Some Juvenile Arthritis, Other Indications

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The U.S. Food and Drug Administration (FDA) has approved ACTPen, a single-dose, pre-filled autoinjector of Actemra (tocilizumab) to be administered in children 2 and older who have active polyarticular juvenile idiopathic arthritis (PJIA) ... Read more

November 16, 2018November 16, 2018

In JIA, Abnormality of Blood Cells is Seen in Bone Marrow, Researchers Find

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Disrupted blood cell production and markedly high rates of inflammation are seen in patients with juvenile idiopathic arthritis (JIA), Chinese researchers report. The study, “Characteristics of bone marrow cells in ... Read more